Come Hands in Loose Games

In contrast to other semi-bluff hands and small pairs, come hands increase in value with many players in the pot because you are usually getting excellent pot odds to draw to them. Furthermore, when the game is loose, you figure to get paid off well once you've made a straight or a flush. Therefore, in a loose game with several players in the pot, you should play more drawing hands, such as big three-flushes on fourth street in seven-card stud, than you would usually play.
In loose games, then, you should tighten up considerably on semi-bluffs but loosen up with legitimate hands. However, you would not play loose with marginal hands like two small pair or one medium pair when several opponents are in the pot.